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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
25.45
Human Site:
Y341
Identified Species:
46.67
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y341
M
N
Q
A
S
E
F
Y
L
A
S
S
P
P
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y343
M
N
E
A
K
D
F
Y
L
A
T
S
P
P
D
Dog
Lupus familis
XP_546691
722
81319
Y511
M
N
Q
A
S
E
F
Y
L
A
S
S
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y341
M
N
Q
A
S
E
F
Y
L
A
S
S
P
P
S
Rat
Rattus norvegicus
Q09137
552
62239
Y341
M
N
Q
A
S
E
F
Y
L
A
S
S
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
Y312
M
N
E
A
K
D
F
Y
L
A
T
S
P
P
D
Chicken
Gallus gallus
Q9IA88
798
88848
F418
N
P
L
Q
P
V
F
F
P
V
D
P
N
F
N
Frog
Xenopus laevis
NP_001088426
560
64038
Y352
M
N
E
A
K
D
F
Y
L
A
T
S
P
P
D
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G435
M
A
L
D
S
D
E
G
E
E
P
S
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
E309
K
F
N
V
K
E
A
E
V
H
S
A
L
L
G
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
E409
D
N
K
R
I
A
D
E
T
A
K
L
S
I
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
N332
I
N
M
G
F
D
R
N
H
L
I
E
S
L
R
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
N399
L
I
K
D
M
K
A
N
K
S
V
S
D
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
66.6
93.3
N.A.
100
93.3
N.A.
66.6
6.6
66.6
26.6
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
86.6
20
86.6
40
N.A.
N.A.
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
54
0
8
16
0
0
62
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
39
8
0
0
0
8
0
8
0
24
% D
% Glu:
0
0
24
0
0
39
8
16
8
8
0
8
0
16
8
% E
% Phe:
0
8
0
0
8
0
62
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
8
0
16
0
31
8
0
0
8
0
8
0
0
0
0
% K
% Leu:
8
0
16
0
0
0
0
0
54
8
0
8
8
16
8
% L
% Met:
62
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
70
8
0
0
0
0
16
0
0
0
0
8
0
8
% N
% Pro:
0
8
0
0
8
0
0
0
8
0
8
8
62
54
0
% P
% Gln:
0
0
31
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
39
0
0
0
0
8
39
70
16
0
16
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
24
0
0
0
16
% T
% Val:
0
0
0
8
0
8
0
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _